Academic publishing riposte. Do not shoot the messenger

Cell signalling in pulmonary vascular cells: do not shoot the messenger!

Pulmonary hypertension is associated with pulmonary vascular remodelling, rendering the vessels unresponsive to vasodilators. An understanding of the mechanisms which cause this remodelling is required, which is likely to be linked to changes in vascular tone whether stimulated by hypoxia or other factors. One way to approach this is to try to understand the intracellular signalling pathways as...

What academic publishing can do for science?

Don't Shoot the Messenger

The incredible fervor surrounding the recent publication of articles calling into question the evidence of benefit for mass deworming treatment highlights the passion and commitment of the neglected tropical disease community. This is not simply an academic debate. This conversation highlights very real tensions within the global health community between the need for continued advocacy to ensur...

Don't shoot the messenger.

Regarding prostate-specific antigen: let's not shoot the messenger.

It is well known that androgens drive prostate cancer and the inhibition of 5a-reductase results in an inhibition of the conversion of testosterone to dihydrotestosterone, the active androgen in the prostate. Recently, two large prospective randomized trials have tested the 5a-reductase inhibitors, finasteride and dutasteride compared to placebo for the chemoprevention of prostate cancer in mid...